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Inogent has created capabilities to handle process development involving wide range of chemistry like Azides, Nitration, Chiral Synthesis, Cryogenic
Rxns, Enzymatic Reactions, Decarboxylation, Cyanation, Bromination, Grignard, Chlorination, Diazotization, Acetylation , Reduction, Methylation, Oxidation etc.
The development capabilities are matched with capacities in Kilo Lab and Pilot Plant to scale up molecules to suit the supply requirements for various clinical
phases from 1 Kg to 100 Kg levels. |
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| Facilities: |
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| One to Tens of Kg scale |
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Glass Reactors, SS, Hastelloy & Glass lined reactors |
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Capacities ranging from 20 - 250 L (5 - 66 US gal) |
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Individual suites for reactors |
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Wide range of reaction temperatures ((-70 to 200 deg C) |
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Necessary support equipment for filtration, drying, milling, sieving etc. |
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| Tens to Hundreds of Kg scale |
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SS, Glass & Glass lined reactors |
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Flexible lay out of reactors |
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Wide range of reaction temperatures ((-70 to 200 deg C) |
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Capacities ranging from 50 L - 2000 L
Total Capacity 8 KL |
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Capacities ranging from 100 – 1000 L (26-2640 US gal) |
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Operating Pressure up to 20 Bar |
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Capability to handle cryogenic conditions at acidic pH |
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| For effective combination of cost and capability advantage, new state of the art manufacturing
facility is under construction. This is a cGMP compliant custom manufacturing block and will get commissioned in March 2010. |
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2 independent modules of Kilo Lab and 1 module of Pilot Plant |
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Kilo Lab: Reactor capacity ranging from 50 L to 200 L. |
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Pilot Plant: Reactor capacity ranging from 250 L to 3000 L. |
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Dedicated powder processing areas – Class 100,000 |
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Necessary supporting equipment |
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Utilities including Cryogenic (-85 C) |
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Hot Oil (250 C) and Huber system (-85 to +200 deg C) |
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Vacuum system (0.1 Torr) and Purified Water – USP 30 |
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